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Volume 19, Issue 6 , Pages 339-346 , July 2010

ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: A systematic review and meta-analysis

B.S. Haerian
- Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
- Corresponding author.
H. Roslan
- UKM Medical Molecular Biology Institute, National University of Malaysia, Kuala Lumpur, Malaysia
A.A. Raymond
- Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia
C.T. Tan
- Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
K.S. Lim
- Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
S.Z. Zulkifli
- UKM Medical Molecular Biology Institute, National University of Malaysia, Kuala Lumpur, Malaysia
E.H.M. Mohamed
- Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
H.J. Tan
- Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia
Z. Mohamed
- Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Received 14 March 2010 ,Revised 30 April 2010 ,Accepted 7 May 2010.

Results of the published studies of the association between ABCB1 C3435T polymorphism and drug-resistance in epilepsy. Areas of squares of individual studies are inversely proportional to the variance

Results of the published studies of the association between ABCB1 C3435T polymorphism and drug-resistance in epilepsy. Areas of squares of individual studies are inversely proportional to the variances of the log ORs and the horizontal lines represent 95% CI estimating the outcome of the C allele against the T allele. The study of Szoeke et al. is divided into three sub-studies for Scotland (a), Australia (b), and Hong Kong (c).
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