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Volume 19, Issue 5 , Pages 296-299 , June 2010

Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats

Giangennaro Coppola
- Clinic of Child Neuropsychiatry, Second University of Naples, Italy
- Corresponding author at: Clinic of Child and Adolescent Neuropsychiatry, Department of Psychiatry, Second University of Naples, Via Pansini 5, Naples, Italy. Tel.: +39 081 5666695; fax: +39 081 5666694.
Salvatore Arcieri
- Clinic of Child Neuropsychiatry, Second University of Naples, Italy
Alfredo D’Aniello
- Clinic of Child Neuropsychiatry, Second University of Naples, Italy
Tullio Messana
- Clinic of Child Neuropsychiatry, Second University of Naples, Italy
Alberto Verrotti
- Section of Pediatrics, Department of Pediatrics, University of Chieti, Italy
Giuseppe Signoriello
- Department of Public Health, Second University of Naples, Italy
Antonio Pascotto
- Clinic of Child Neuropsychiatry, Second University of Naples, Italy

Received 17 November 2009 ,Revised 28 February 2010 ,Accepted 18 March 2010.

Latency (seconds) of different seizure types in the three groups of rats. *p≤0.02 (Dunnett t-test, two-sided (seizure latency in controls vs. the other groups).

Latency (seconds) of different seizure types in the three groups of rats. *p≤0.02 (Dunnett t-test, two-sided (seizure latency in controls vs. the other groups).
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Mean duration of seizure 1 and 2 after s.c. PTZ 70mg/kg in Wistar rats. *p≤0.02 (Dunnett t-test, two-sided; seizure type 2 in controls vs. the other groups).

Mean duration of seizure 1 and 2 after s.c. PTZ 70mg/kg in Wistar rats. *p≤0.02 (Dunnett t-test, two-sided; seizure type 2 in controls vs. the other groups).
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