Seizure: European Journal of Epilepsy
Volume 19, Issue 4 , Pages 237-241 , May 2010

Association of alpha subunit of GABAA receptor subtype gene polymorphisms with epilepsy susceptibility and drug resistance in north Indian population

  • Ritu Kumari

      Affiliations

    • Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
    • ,
  • Ram Lakhan

      Affiliations

    • Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
    • ,
  • J. Kalita

      Affiliations

    • Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    • ,
  • U.K. Misra

      Affiliations

    • Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow 226014, India
    • ,
  • Balraj Mittal

      Affiliations

    • Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, India
    • Corresponding Author InformationCorresponding author. Tel.: +91 522 2668700x2322; fax: +91 522 2668017.

Received 5 October 2009 ,Revised 21 February 2010 ,Accepted 26 February 2010.

  • Image Result

    (a) Schematic diagram showing location of GABRA1 gene polymorphisms. (b) Schematic diagram showing location of GABRG2 gene polymorphisms.

    (a) Schematic diagram showing location of GABRA1 gene polymorphisms. (b) Schematic diagram showing location of GABRG2 gene polymorphisms.

  • Image Result

    Representative gel picture for GABRA1 IVS11+15 A>G (rs2279020) genotyping; lane 1, 50bp DNA ladder; lane 2, homozygous AA genotype; lane 3, heterozygous AG genotype; lane 4, homozygous GG genotype.

    Representative gel picture for GABRA1 IVS11+15 A>G (rs2279020) genotyping; lane 1, 50bp DNA ladder; lane 2, homozygous AA genotype; lane 3, heterozygous AG genotype; lane 4, homozygous GG genotype.

  • Image Result
    Representative gel picture for GABRG2 588C>T (rs211037) genotyping. Lane 1, undigested; lane 2, DNA ladder; lane 3, homozygous CC genotype; lane 4, heterozygous CT genotype; lane 5, homozygous TT g

    Representative gel picture for GABRG2 588C>T (rs211037) genotyping. Lane 1, undigested; lane 2, DNA ladder; lane 3, homozygous CC genotype; lane 4, heterozygous CT genotype; lane 5, homozygous TT genotype.

PII: S1059-1311(10)00052-X

doi: 10.1016/j.seizure.2010.02.009

Seizure: European Journal of Epilepsy
Volume 19, Issue 4 , Pages 237-241 , May 2010

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