Seizure: European Journal of Epilepsy
Volume 19, Issue 3 , Pages 198-201 , April 2010

Thalamic activation and cortical deactivation during typical absence status monitored using [18F]FDG-PET: A case report

  • Leonilda Bilo

      Affiliations

    • Epilepsy Center, Department of Neurological Sciences, “Federico II” University, Naples, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 0817464249; fax: +39 0817464249.
  • ,
  • Roberta Meo

      Affiliations

    • Neurology Outpatients Service, Azienda Sanitaria Locale Napoli 1, Naples, Italy
  • ,
  • Maria Fulvia de Leva

      Affiliations

    • Epilepsy Center, Department of Neurological Sciences, “Federico II” University, Naples, Italy
  • ,
  • Caterina Vicidomini

      Affiliations

    • Institute of Biostructure and Bioimaging, CNR and Department of Biomorphological Sciences, “Federico II” University, Naples, Italy
  • ,
  • Marco Salvatore

      Affiliations

    • Institute of Biostructure and Bioimaging, CNR and Department of Biomorphological Sciences, “Federico II” University, Naples, Italy
  • ,
  • Sabina Pappatà

      Affiliations

    • Institute of Biostructure and Bioimaging, CNR and Department of Biomorphological Sciences, “Federico II” University, Naples, Italy

Received 23 August 2009 ,Revised 12 January 2010 ,Accepted 15 January 2010.

References 

  1. Aghakhani Y, Bagshaw AP, Bénar CG, Hawco C, Andermann F, Dubeau F, et al. fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain. 2004;127:1127–1144
  2. Blumenfeld H. From molecules to networks: cortical/subcortical interactions in the pathophysiology of idiopathic generalized epilepsy. Epilepsia. 2003;44:7–15
  3. Duncan JS. Brain imaging in idiopathic generalized epilepsies. Epilepsia. 2005;46:108–111
  4. Engel J, Lubens P, Kuhl DE, Phelps ME. Local cerebral metabolic rate for glucose during petit mal absences. Ann Neurol. 1985;17:121–128
  5. Gotman J, Grova C, Bagshaw A, Kobayashi E, Aghakani Y, Dubeau F. Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain. Proc Natl Acad Sci USA. 2005;102:15236–15240
  6. Panayiotopoulos CP. Absence Status Epilepticus. 2005;http://www.ilae-epilepsy/Visitors/Centre/ctf/absence_status.cfm
  7. Prevett MC, Duncan JS, Jones T, Fish DR, Brooks DJ. Demonstration of thalamic activation during typical absence seizures using H2(15)O and PET. Neurology. 1995;45:1396–1402
  8. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci USA. 2001;98:676–682
  9. Salek-Haddadi A, Lemieux L, Merschhemke M, Friston KJ, Duncan JS, Fish DR. Functional magnetic resonance imaging of human absence seizures. Ann Neurol. 2003;53:663–667
  10. Shorvon S, Walker M. Status epilepticus in idiopathic generalized epilepsy. Epilepsia. 2005;46:73–79
  11. Theodore WH, Brooks R, Margolin R, Patronas N, Sato S, Porter RJ, et al. Positron emission tomography in generalized seizures. Neurology. 1985;35:684–690
  12. Thomas P, Valton P, Genton P. Absence and myoclonic status epilepticus precipitated by antiepileptic drugs in idiopathic generalized epilepsy. Brain. 2006;129:1281–1292

PII: S1059-1311(10)00010-5

doi: 10.1016/j.seizure.2010.01.009

Seizure: European Journal of Epilepsy
Volume 19, Issue 3 , Pages 198-201 , April 2010