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Volume 19, Issue 3 , Pages 190-194 , April 2010

Unusual consequences of status epilepticus in Dravet syndrome

M. Chipaux
- Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France
- Inserm, U663, Paris, F-75015 France; University Paris Descartes, Paris, F-75015, France
- Corresponding author at: Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France. Tel.: +33 144481536; fax: +33 142192692.
N. Villeneuve
- Centre Saint-Paul, Hôpital Henri Gastaut, Marseille, France
P. Sabouraud
- Hôpital Américain, Service de Pédiatrie A, CHU de Reims, Reims, France
I. Desguerre
- Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France
N. Boddaert
- Service de radiologie pédiatrique, AP-HP, Hôpital Necker Enfants Malades, Paris, France
C. Depienne
- UF de neurogénétique moléculaire et cellulaire, Hôpital Pitié-Salpétrière, Paris, France
C. Chiron
- Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France
- Inserm, U663, Paris, F-75015 France; University Paris Descartes, Paris, F-75015, France
O. Dulac
- Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France
- Inserm, U663, Paris, F-75015 France; University Paris Descartes, Paris, F-75015, France
R. Nabbout
- Service de neuropédiatrie, Centre de référence épilepsies rares, AP-HP, Hôpital Necker Enfants Malades, Paris, France
- Inserm, U663, Paris, F-75015 France; University Paris Descartes, Paris, F-75015, France

Received 30 June 2009 ,Revised 7 January 2010 ,Accepted 15 January 2010.

MRI of patient 1 before (age 3 months) (a) and 2 months after complicated SE (age 13 months) (b).

MRI of patient 1 before (age 3 months) (a) and 2 months after complicated SE (age 13 months) (b).
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MRI of patients 2 and 3 after complicated SE (a, b) on T2 weighted sequence compared to normal (c) and acute anoxic-ischemia at the same age (d). MRIs (a, b) were performed at mean 6 weeks after the e

MRI of patients 2 and 3 after complicated SE (a, b) on T2 weighted sequence compared to normal (c) and acute anoxic-ischemia at the same age (d). MRIs (a, b) were performed at mean 6 weeks after the event. The MRI of patients with DS (a, b) shared severe cortical atrophy similar to that of postanoxic-ischemic lesions but in addition dramatic loss of white matter with slight basal ganglia atrophy.
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