Seizure: European Journal of Epilepsy
Volume 16, Issue 1 , Pages 69-73 , January 2007

Seizures during treatment of Vitamin B12 deficiency

  • G. Benbir

      Affiliations

    • Division of Child Neurology, Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • ,
  • S. Uysal

      Affiliations

    • Division of Child Neurology, Department of Pediatrics, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • ,
  • S. Saltik

      Affiliations

    • Division of Child Neurology, Department of Pediatrics, Goztepe Hospital, Istanbul, Turkey
    • ,
  • C. Aktuglu Zeybek

      Affiliations

    • Division of Metabolic diseases, Department of Pediatrics, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • ,
  • A. Aydin

      Affiliations

    • Division of Metabolic diseases, Department of Pediatrics, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • ,
  • A. Dervent

      Affiliations

    • Division of Child Neurology, Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • ,
  • C. Yalcinkaya

      Affiliations

    • Division of Child Neurology, Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +90 212 4143157; fax: +90 212 4143164.

Received 3 March 2005 ,Revised 12 September 2005 ,Accepted 31 October 2006.

References 

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  2. Graham SM, Arvela OM, Wise GA. Long-term neurological consequences of nutritional Vitamin B12 deficiency in infants. J Pediatr. 1992;121:710–714
  3. Ozer EA, Turker M, Bakiler AR, Yaprak I, Ozturk C. Involuntary movements in infantile cobalamin deficiency appearing after treatment. Pediatr Neurol. 2001;25:81–83
  4. Grattan-Smith PJ, Wilcken B, Procopis PG, Wise GA. The neurolgical syndrome of infantile cobalamin deficiency: developmental regression and involuntary movements. Movement Disord. 1997;12:39–46
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  11. Lundgren J, Blennow G. Vitamin B12 deficiency may cause benign familial infantile convulsions: a case report. Acta Pediatr. 1999;88:1158–1160
  12. Korenke GC, Hunneman DH, Eber S, Hanefeld F. Severe encephalopathy with epilepsy in an infant caused by subclinical maternal pernicious anaemia: case report and review of the literature. Euro J Pediatr. 2004;163:196–201
  13. Kubova H, Folbergrova J, Mares P. Seizures induced by homocysteine in rats during ontogenesis. Epilepsia. 1995;36:750–756
  14. Mares P, Folbergrova J, Langmeier M, Haugvicova R, Kubova H. Convulsant action of d,l-homocysteic acid and its stereoisomers in immature rats. Epilepsia. 1997;38:767–776
  15. Marangos PJ, Loftus T, Wiesner J, Lowe T, Rossi E, Browne CE, et al. Adenosinergic modulation of homocysteine-induced seizures in mice. Epilepsia. 1990;31:239–246
  16. Folbergrova J. Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats. Exp Neurol. 1997;145:442–450
  17. Folbergrova J, Haugvicova R, Mares P. Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists. Exp Neurol. 2000;161:336–345
  18. Akaike A, Tamura Y, Sato Y, Yokota T. Protective effects of a Vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons. Euro J Pharmacol. 1993;241:1–6

PII: S1059-1311(06)00203-2

doi: 10.1016/j.seizure.2006.10.016

Seizure: European Journal of Epilepsy
Volume 16, Issue 1 , Pages 69-73 , January 2007

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